A detailed simulation of part of the brain has been constructed.
(The Blue Brain project was set up to simulate an entire human brain, down to the molecular level, they have now announced that they have constructed a region of the brain, the the neocortical column, molecule by molecule and they say they have observed the first indication of thought. Allegedly scaling it up is only a matter of money. I guess this brings the old adage of "I think therefore I am" into question.)