If you want to do something that no human has ever done before, shuffle a pack of cards.

(When you shuffle a normal pack of 52 playing cards, the number of possible permutations is ‘52 factorial’ otherwise known as 52! or 52 shriek.

This works out as 52 times 51 times 50 … all the way down to one, which gives you the sum of  
80,658,175,170,943,878,571,660,636,856,403,766,975,289,505,440,883,277,824,000,000,000,000.)
Source: QI